TxAgent-T1-Llama-3.1-8B

Maintained By
mims-harvard

TxAgent-T1-Llama-3.1-8B

PropertyValue
Base ModelLlama3.1-8B-Instruct
Training Data378,027 instruction-tuning samples
PaperarXiv:2503.10970
Authormims-harvard
Model HubHugging Face

What is TxAgent-T1-Llama-3.1-8B?

TxAgent-T1-Llama-3.1-8B is a specialized AI model designed for precision therapeutics, leveraging multi-step reasoning and real-time biomedical knowledge retrieval. Built upon Llama3.1-8B-Instruct, this model integrates a toolbox of 211 tools to provide comprehensive analysis of drug interactions, contraindications, and patient-specific treatment recommendations.

Implementation Details

The model is trained on TxAgent-Instruct dataset, comprising three key components: a tooling dataset with 211 augmented tools, 85,340 therapeutic questions, and detailed reasoning traces encompassing 177,626 reasoning steps and 281,695 function calls. The training data is carefully curated from FDA drug labeling documents and verified biomedical sources, excluding post-2023 drug approvals to maintain evaluation integrity.

  • Achieves 92.1% accuracy in drug reasoning tasks
  • Outperforms GPT-4 by up to 25.8%
  • Maintains < 0.01 variance across drug name variants
  • Integrates 211 biomedical tools from trusted sources

Core Capabilities

  • Multi-step reasoning for drug interaction analysis
  • Real-time biomedical knowledge retrieval
  • Personalized treatment recommendation generation
  • Cross-source validation of therapeutic decisions
  • Comprehensive drug contraindication assessment

Frequently Asked Questions

Q: What makes this model unique?

TxAgent-T1-Llama-3.1-8B stands out for its integration of multi-step reasoning with real-time biomedical knowledge and tool-assisted decision-making. It's specifically designed for therapeutic tasks and can maintain high accuracy across different drug naming conventions.

Q: What are the recommended use cases?

The model is ideal for analyzing drug interactions, evaluating treatment strategies, identifying contraindications based on patient characteristics, and providing evidence-based therapeutic recommendations. It's particularly useful in scenarios requiring complex medical reasoning and cross-validation of multiple biomedical sources.

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